- Economic Impact
- Nano Network
Professor, Department of Molecular Microbiology and Immunology, Oregon Health Sciences University
The Barklis lab studies the assembly, structure, and replication of viruses in vivo and in vitro, using a combination of molecular biology, biophysical, and imaging techniques. The goals of the lab are to develop antivirals based on structure-function relationships; and to determine the structures of macromolecular complexes, and the mechanisms of their assembly. In terms of nanotechnology, the Barklis lab uses novel electron microscopy and fluorescence microscopy methods for the analysis of structures composed of proteins, nucleic acids and/or membranes. The lab also has an interest in using membranes, nucleic acids, peptides and proteins as surfaces on which to assemble ordered structures.