ONAMI | Markus Grompe

Researchers

Markus Grompe

Professor, Ray Hickey Chair of Pedriatric Research, Oregon Stem Cell Center, Oregon Health Sciences University

Thrusts

NanoBiotechnology/NanoMedicine

Biography

Dr. Grompe received his medical degree (Dr. med.) in 1982 at the University of Ulm Medical School in Germany. From 1984-1987 Dr. Grompe was trained in Pediatrics at Oregon Health Sciences University in Portland, Oregon, USA and then moved to Baylor College of Medicine in Houston, Texas. There he was a fellow sponsored by the Pediatric Scientist Training Program in the Institute for Molecular Genetics from 1987-1991 and worked on gene therapy for inherited diseases, particularly metabolic liver disorders.

In 1991, Dr. Grompe joined the faculty at Oregon Health & Science University and he is currently Professor in the Departments of Molecular and Medical Genetics and Pediatrics. He is a recipient of the E. Mead Johnson award for pediatric research (2002) and the Merit Award of the Fanconi Anemia Research Foundation (2002). He is involved in the clinical care of patients with genetic diseases as well as scientific investigation. In 2004 he became the first director of the newly founded Oregon Stem Cell Center.

Research:  Single gene disorders, although individually rare, cumulatively represent a significant medical burden, particularly in the pediatric age group. Current treatment options are very limited and outcomes remain poor in many cases. Gene transfer and cell therapy (including stem cell transplantation) are hopeful strategies for future therapies. Its is our long-term goal to develop these into clinically useful procedures. Our particular focus are metabolic liver diseases and the DNA repair disease Fanconi Anemia.

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